Primary Targets

The primary targets of CCHD screening are the “Cyanotic Seven” diseases. Pulse oximetry screening may also pick up other heart malformations and non-cardiac causes of cyanosis.

The Cyanotic Seven

• Hypoplastic left heart syndrome
• Pulmonary atresia with intact septum
• Total anomalous pulmonary venous return
• Transposition of the great arteries
• Truncus arteriosus
• Tetralogy of Fallot
• Tricuspid atresia

Secondary targets

• Coarctation of the aorta
• Double outlet right ventricle
• Ebstein’s anomaly
• Interrupted aortic arch
• Single ventricles

Additional non-cardiac causes of cyanosis potentially identified by CCHD screening

• Infection
• Persistent Pulmonary Hypertension of the Infant (PPHN)
• Respiratory Illnesses