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Newborn Screening Ontario


Find a Follow-Up Centre

London/Southwestern Ontario

LHSC- Children’s Hospital of Western Ontario

800 Commissioners Road East

N6C 2V5 London , ON


Phone: (519) 685-____


Hamilton/Central South and Central West

Hamilton Health Sciences Centre/McMaster University Medical Centre

Symptomatic cCMV Infection

What does being symptomatic with cCMV infection mean?

The majority of infants with cCMV infection never develop symptoms of the infection.   If your baby is described as having symptoms of cCMV infection, they could have already had or may currently have one or more of the following features:

·         Jaundice (yellow skin and eyes)

·         Small head (microcephaly)

Screen Positive Follow-Up

Why has my baby been referred to an Infectious Diseases (ID) Clinic?

Your baby has had a screen positive result (CMV detected) on their hearing loss risk factor blood spot screen.  Their positive result indicated a high chance of having congenital cytomegalovirus (cCMV) infection.  Infectious Diseases specialists are experts in the care of infants with cCMV infections.


What can I expect from the first appointment?

CMV Detected

What does a screen positive result mean?

A screen positive result means that your child most likely has cCMV infection.  However, this still needs to be confirmed through other diagnostic testing.

If your child has:

·         Hearing loss and confirmed cCMV infection – cCMV could be the cause for your child's hearing loss


·         Normal hearing test and confirmed cCMV infection – your child still has a ~10% risk of developing early childhood hearing loss


What happens next?

Cytomegalovirus (CMV)

What is cytomegalovirus (CMV)?

CMV is a common virus.  Most healthy people will not have any signs or symptoms and will not know they have had it.  When a pregnant woman is infected there is a risk of infection of the baby.  When this happens it is called congenital CMV infection.


How common is CMV?

Screen Negative Result

What did the hearing loss risk factor blood spot screen rule out?

The hearing loss risk factor blood spot screen is a screen for cCMV infection.  It cannot rule out cCMV infection entirely as the sensitivity is less than 100%.  This means that a small number of cases of cCMV infection will not be detected through screening. 

If your child’s doctor has any concerns regarding possible cCMV infection, we would recommend additional forms of testing for CMV.